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ribociclib will boost the stage or impact of diazepam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.cenobamate will improve the stage or influence of diazepam by influencing hepatic enzyme CYP2C19 metabolism. Modify Therapy/Keep track of Closely. Look at a dose reduction of CYP2C19 substrates, as clinically suitable,